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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
7.27
Human Site:
T1636
Identified Species:
12.31
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
T1636
Q
N
I
S
W
K
K
T
I
V
T
R
F
L
K
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
T1636
Q
N
I
S
W
K
K
T
I
V
T
R
F
L
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
K1635
Q
N
T
S
W
K
K
K
I
V
Y
R
F
L
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
K1635
Q
H
T
F
W
R
K
K
M
V
H
R
F
L
K
Rat
Rattus norvegicus
NP_001101888
2143
241191
K1635
H
S
T
F
W
K
K
K
M
V
H
R
F
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
S1648
Q
R
T
K
W
Q
K
S
Q
V
R
Q
L
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
E1636
Q
R
T
K
W
L
K
E
Q
I
T
A
L
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
G1587
Q
S
N
A
E
H
F
G
V
L
F
A
P
L
Q
Honey Bee
Apis mellifera
XP_393800
2028
231830
Q1523
T
L
I
D
S
L
L
Q
I
I
P
A
K
E
K
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
G1196
S
P
G
S
S
V
A
G
G
R
G
N
R
G
H
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
V1181
A
R
L
I
D
L
Q
V
D
T
H
N
S
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
K1524
S
G
H
P
I
F
R
K
C
L
A
A
V
A
E
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
A1315
V
I
L
N
T
M
T
A
L
V
S
K
Y
G
K
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
A1334
V
N
C
V
D
K
I
A
E
K
Y
G
K
K
D
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
80
N.A.
53.3
53.3
N.A.
N.A.
33.3
N.A.
33.3
N.A.
13.3
20
6.6
0
P-Site Similarity:
100
100
N.A.
80
N.A.
73.3
66.6
N.A.
N.A.
60
N.A.
46.6
N.A.
46.6
26.6
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
53.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
8
15
0
0
8
29
0
15
0
% A
% Cys:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
15
0
0
0
8
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
8
0
0
8
8
0
0
0
0
8
22
% E
% Phe:
0
0
0
15
0
8
8
0
0
0
8
0
36
0
0
% F
% Gly:
0
8
8
0
0
0
0
15
8
0
8
8
0
15
0
% G
% His:
8
8
8
0
0
8
0
0
0
0
22
0
0
0
8
% H
% Ile:
0
8
22
8
8
0
8
0
29
15
0
0
0
0
0
% I
% Lys:
0
0
0
15
0
36
50
29
0
8
0
8
15
8
50
% K
% Leu:
0
8
15
0
0
22
8
0
8
15
0
0
15
58
0
% L
% Met:
0
0
0
0
0
8
0
0
15
0
0
0
0
0
0
% M
% Asn:
0
29
8
8
0
0
0
0
0
0
0
15
0
0
0
% N
% Pro:
0
8
0
8
0
0
0
0
0
0
8
0
8
0
0
% P
% Gln:
50
0
0
0
0
8
8
8
15
0
0
8
0
0
8
% Q
% Arg:
0
22
0
0
0
8
8
0
0
8
8
36
8
0
0
% R
% Ser:
15
15
0
29
15
0
0
8
0
0
8
0
8
0
0
% S
% Thr:
8
0
36
0
8
0
8
15
0
8
22
0
0
0
8
% T
% Val:
15
0
0
8
0
8
0
8
8
50
0
0
8
0
0
% V
% Trp:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
15
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _